Blar i forfatter "Wüst, Rob C.I."

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    • Altered mitochondrial metabolism in the insulin-resistant heart 

      Makrecka-Kuka, Marina; Liepinsh, Edgars; Murray, Andrew J.; Lemieux, Hélène; Dambrova, Maija; Tepp, Kersti; Puurand, Marju; Käämbre, Tuuli; Han, Woo H.; de Goede, Paul; O'Brien, Katie A.; Turan, Belma; Tuncay, Erkan; Olgar, Yusuf; Rolo, Anabela P.; Palmeira, Carlos M.; Boardman, Neoma Tove; Wüst, Rob C.I.; Larsen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-16)
      Obesity‐induced insulin resistance and type 2 diabetes mellitus can ultimately result in various complications, including diabetic cardiomyopathy. In this case, cardiac dysfunction is characterized by metabolic disturbances such as impaired glucose oxidation and an increased reliance on fatty acid (FA) oxidation. Mitochondrial dysfunction has often been associated with the altered metabolic function ...

    • Intra-cellular to inter-organ mitochondrial communication in striated muscle in health and disease 

      Boardman, Neoma Tove; Wüst, Rob C.I. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-02)
      Mitochondria sense both biochemical and energetic input in addition to communicating signals regarding the energetic state of the cell. Increasingly, these signaling organelles are recognized as key for regulating different cell functions. This review summarizes recent advances in mitochondrial communication in striated muscle, with specific focus on the processes by which mitochondria communicate ...